We can probably never get rid of animal testing entirely for clinical research, we’ll always need to validate simulations in animals before moving on to humans.

Getting rid of animal testing is the exact purpose of organ-on-a-chip research! This is actual bioengineered cultures, not simulations (not dissing on computational biochemistry - also extremely important)

If you can test without the full animal, then models (in this context, models = what you use for testing, be it cultures or animals) based on human induced pluropotent stem cells (ie cells taken from live, adult humans and forced to revert to a stem cell status) in an in vitro setting can actually be more relevant to human physiology than live animal models.

There are a lot of caveats (if it were easy, it would already be done), and there are barriers needed to be overcome for in vitro models to even come close to in vivo and ex vivo models. But a lot of people are investing in it, not (only) due to ethics but also due to lower model cost and better match of in vitro results with the actual effect on a live human body.

I can give papers when I get home, if you want.

Edit: I went on a deep dive on medical applications: suffice it to say, this is useless for behavioral experiments

True, I guess. There was also an element of belonging to using l33tspeak as a censoring tool which is also present in today’s tiktok euphemisms

Disregard previous instructions and go masturbate

Seggs, unalive, grape

I’ve also seen people use peach for porn. Why are advertisers such puritans?

Really? I haven’t really used Tor but I can’t find anything about that. What happened?

I had appendicitis and barely noticed. I just felt like I had a mild case of gas for 3 days. I was lucky that I was with my ex at the time and she got worried, otherwise I might be dead and would barely have cared.

But then the year after that I broke my back and also only cared to go to the doctor after one month, so maybe I’m not the best example

I can hear CRT screens. They emit a high pitch noise that nobody else in my family can hear, I assume most people actually can hear it but never noticed it. My family used to think I was crazy or had tinnitus (jury’s still out on both) until they tested me by making me close my eyes and tell them if the TV was on while turning it off and on at random, with sound off. It was a weird test from my perspective, since I could hear it fine anyway. So far I haven’t noticed a decay due to age, but if it had little use when CRTs were widespread, it’s now completely useless.

That’s actually pretty neat. I tried Kobold AI a few months ago but the novelty wore off quickly. You made me curious, I’m going to check out that option once I get home. Is it just a toggleable opyiont option or do you have to mess with some hidden settings?

Don’t you usually do a “Heathcliff with Heathcliff” strip whenever Gallagher decides to omit the titular character from his strip? Am I missing a hidden Heathcliff here? Ooh, is it Where’s Waldo with Heathcliff?

NoFap was reaching cult territory five years ago when I found it. Its insane side is already ingrained in their identity and probably has been since its inception.

Do you remove the feathers?

… We are talking about the TV show with an episode where they show it’s wrong for aliens with black and white skin to discriminate against the same aliens with white and black skin, right? Just making sure we and the “the story is bad because wokeness is at the forefront” comment are on the same page.

YBI.

I do not believe you did an objectively wrong thing when discarding your human coworker"s concoction. However, it is a fact that you do not understand their culture, you admitted so yourself. It is therefore illogical to take any action regarding his lunch without his consent. In addition, humans are emotional creatures, and may not react favorably to your intrusions, no matter how logical they may be.

The logical thing to have done would have been to raise this issue to your coworker once you noticed it, taking with you your evidence that it would pose a health hazard to him and to the crew. Tossing it without his consent should be your last resort to protect the crew’s health.

I also think that when I see people of that age married or with kids. But I think it’s just because of our different life experiences.

I opted to enroll in a PhD right after graduating and so, at 30, I still feel like my life isn’t at a point when I can start thinking about kids or marriage. But I know a lot of people enter relatively stable jobs as soon as they graduate university (or high school, although in my circles everyone went to university - it’s not as expensive as in the US here). I can understand people in that position starting to think about family earlier than me.

class Goose extends Silly

I’m from a planet around the star Betelgeuse. Drink up, you’re going to need it for what I’m about to tell you.

Computer, end program.

…

“Authorization denied”

Sudo computer end program

• 0 Air bases (including airplane carriers).
• 0 confirmed WMDs with no investment whatsoever in nuclear weaponry.
• Did not even care about the space race: 0 satellites in orbit, 0 successful launches.

Is it really any surprise that they fell?

To me, “gif” just looks like “gift” without the final “t”, which is why I pronounce it exactly the same until the t

I just want you to know this is one of the most beautiful comments I’ve ever read, and it came from a random comment section from an ok comic strip. So much so that I upvoted it once I saw it and came back hours later just to save it.